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Proceedings of

9th International Conference On Advances In Applied Science And Environmental Technology ASET 2019

"ASSESSING THE BIOPRINTABILITY OF SELF-ASSEMBLING PEPTIDE BIOINKS IN TERMS OF STRUCTURE FIDELITY AND CELL VIABILITY"

CHARLOTTE A. E. HAUSER DANA ALHATTAB FRANCESCA MELLE KOWTHER KAHIN
DOI
10.15224/978-1-63248-174-0-03
Pages
8 - 14
Authors
4
ISBN
978-1-63248-174-0

Abstract: “Organ donor shortage as well as an increasing demand for personalized medicine have opened up new avenues in tissue engineering. As 3D bioprinting may provide promising solutions, bioinks of different compositions are being developed to serve bioprinting needs. As for the development of suitable bioinks, certain challenges and limitations still exist including: The use of inorganic, unnatural or undefined natural materials, UV and chemical crosslinking for gelation, and fidelity of 3D structures. Self-assembling peptides boast an advantage of resembling human-like materials and activating instantaneous gelation. In this paper, ultrashort peptides are used for 3D bioprinting. The printed scaffolds are analyzed for structure fidelity, cell viability, and proliferation. The results are compared with commercial Biogelxâ„¢ peptide bioinks as a benchmark. Our custom-designed robotic 3D bioprinter is used and compared with the commercial Inkredible+ bioprinter. Our results prove the bioprinta”

Keywords: 3D bioprinting, peptide, Biogelx, biomaterials, bioinks, tissue engineering3D bioprinting, peptide, BiogelxŒ, biomaterials, bioinks, tissue engineering

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